課程資訊
課程名稱
生物統計原理
Principles of Biostatistics 
開課學期
112-1 
授課對象
公共衛生學院  全球衛生碩士學位學程  
授課教師
吳亞克 
課號
MGH7048 
課程識別碼
853EM0480 
班次
 
學分
2.0 
全/半年
半年 
必/選修
必修 
上課時間
星期一6,7(13:20~15:10) 
上課地點
公衛105 
備註
本課程以英語授課。全球衛生學程必修課,外系所學生欲選修者請先洽詢主授教師。
限本系所學生(含輔系、雙修生) 且 限公衛學院學生(含輔系、雙修生)
總人數上限:22人 
 
課程簡介影片
 
核心能力關聯
核心能力與課程規劃關聯圖
課程大綱
為確保您我的權利,請尊重智慧財產權及不得非法影印
課程概述

The aim of this course is to introduce basic concepts of statistical analysis commonly used in public health and give some introduction to programming. The practical sessions will be given alongside lectures. The course consists of two parts: the "analytical method", which will provide an introduction of fundamental statistical methods used to extract hidden information in data, and "practical sessions" which will involve problem solving from the biostats and practice in programming on example of R, a freely available statistical software. Real-life examples from each aspect of global health research topics and latest literature are illustrated in the course. 

課程目標
At the end of the course, the students are expected to

1. Explain public health history, philosophy and values (D17-1)

2. Explain the role of quantitative and qualitative methods and sciences in describing and assessing a population’s health (D17-3)

3. Analyze epidemiological data as illustrative examples for R programming 
課程要求
The slides of each lecture and scientific papers for discussion will be available on the course website for students to download before each class. A preceding e-mail for calling sick before a lecture is essential. 
預期每週課後學習時數
 
Office Hours
備註: To be decided 
指定閱讀
 
參考書目
1. [Pa] Pagano M, Gauvreau K, Mattie H. Principles of Biostatistics. CRC Press. 3rd edition. 2022

2. [DeGr] DeGroot MH, Schervish MJ. Probability and Statistics. Pearson 2011

3. [Ro] Rosner B. Fundamentals of Biostatistics. Brooks / Cole. 2015

4. Crawley MJ. The R book. Wiley 2012

5. The Epidemiologist R Handbook https://www.epirhandbook.com/en/index.html 
評量方式
(僅供參考)
   
針對學生困難提供學生調整方式
 
上課形式
作業繳交方式
考試形式
其他
由師生雙方議定
課程進度
週次
日期
單元主題
Week 1
9/4  Introduction, descriptive statistics, mean / median / variance
[Pa] Ch. 5, 8-9 
Week 2
9/11  Central characteristics.
Random numbers. Probabilities  
Week 3
9/18  Discrete and continuous distributions
 
Week 4
9/25  Sampling process. Bayes rule
Practical exercise 
Week 5
10/2  Statistical testing
[Ro] Ch. 7 
Week 6
10/9  *National holiday* 
Week 7
10/16  Statistical testing (cont’)
[Ro] Ch. 7–8 
Week 8
10/23  Midterm exam 
Week 9
10/30  Power of the test. Sample size determination
Linear regression models
[Ro] Ch. 10–11; [DeGr] Ch. 10.1–10.3 
Week 10
11/6  Generalized linear models 
Week 11
11/13  Introduction to survival analysis 
Week 12
11/20  Meta-analysis 
Week 13
11/27  Introduction to R programming 
Week 14
12/4  Working with data frames 
Week 15
12/11  Working with ggplot 
Week 16
12/18  Practice in R / Final project